INT182508

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Context Info
Confidence 0.26
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.13
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (AGTR2) signal transducer activity (AGTR2)
Anatomy Link Frequency
pancreas 3
carotid body 1
AGTR2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 198 95.68 Very High Very High Very High
Inflammatory response 6 93.76 High High
cytokine 24 80.36 Quite High
fibrosis 12 63.36 Quite High
antagonist 15 27.96 Quite Low
Arthritis 3 9.84 Low Low
ischemia 3 5.28 Low Low
chemokine 15 5.00 Very Low Very Low Very Low
cINOD 9 5.00 Very Low Very Low Very Low
Inflammatory mediators 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 84 99.80 Very High Very High Very High
Hypoxia 42 99.48 Very High Very High Very High
Injury 27 98.80 Very High Very High Very High
INFLAMMATION 213 95.68 Very High Very High Very High
Hypertension 12 86.96 High High
Stress 30 79.44 Quite High
Apoptosis 6 73.60 Quite High
Fibrosis 9 63.36 Quite High
Cancer 273 62.16 Quite High
Carcinoma 9 59.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Significant evidence has been shown that AT1 receptors are upregulated during disease and that AT2 receptor expression follows behind AT1 expression during injury and healing.
Positive_regulation (follows) of Gene_expression (expression) of AT2 receptor associated with injury and disease
1) Confidence 0.26 Published 2004 Journal J Inflamm (Lond) Section Body Doc Link PMC1074345 Disease Relevance 0.86 Pain Relevance 0.37
Hypoxia has been demonstrated to induce the expression of both AT1b (AT1a and AT1b are subsets of AT1) and AT2 receptors in the rat carotid body and pancreas [39,40].
Positive_regulation (induce) of Gene_expression (expression) of AT2 in pancreas associated with hypoxia
2) Confidence 0.26 Published 2004 Journal J Inflamm (Lond) Section Body Doc Link PMC1074345 Disease Relevance 1.13 Pain Relevance 0.05
Hypoxia has been demonstrated to induce the expression of both AT1b (AT1a and AT1b are subsets of AT1) and AT2 receptors in the rat carotid body and pancreas [39,40].
Positive_regulation (induce) of in carotid body Gene_expression (expression) of AT2 in pancreas associated with hypoxia
3) Confidence 0.09 Published 2004 Journal J Inflamm (Lond) Section Body Doc Link PMC1074345 Disease Relevance 1.13 Pain Relevance 0.05

General Comments

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