INT182557

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Context Info
Confidence 0.25
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Ptger2, Trpv1) cytosol (Trpv1) transport (Trpv1)
signal transduction (Ptger2) transmembrane transport (Trpv1) lipid metabolic process (Trpv1)
Anatomy Link Frequency
PGE2 2
Ptger2 (Mus musculus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
IPN 4 97.96 Very High Very High Very High
qutenza 50 90.76 High High
Inflammation 18 84.24 Quite High
Hyperalgesia 3 81.40 Quite High
Pain 7 80.32 Quite High
Inflammatory mediators 3 78.96 Quite High
Thermal hyperalgesia 15 60.88 Quite High
dorsal root ganglion 27 5.00 Very Low Very Low Very Low
withdrawal 5 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Inflammatory Pain 4 97.96 Very High Very High Very High
INFLAMMATION 23 84.24 Quite High
Hyperalgesia 18 81.40 Quite High
Pain 8 80.32 Quite High
Nociception 11 75.00 Quite High
Ganglion Cysts 27 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Hypersensitivity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PGE2 or PGI2increased or sensitized TRPV1 responses through EP1 or IP receptors, respectively predominantly in a PKC-dependent manner in both HEK293 cells expressing TRPV1 and mouse DRG neurons.
PGE2 Regulation (sensitized) of Regulation (responses) of TRPV1 in PGE2
1) Confidence 0.25 Published 2005 Journal Mol Pain Section Abstract Doc Link PMC1074353 Disease Relevance 0.68 Pain Relevance 0.52

General Comments

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