INT182563

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Context Info
Confidence 0.22
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.40
Pain Relevance 1.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ptger2, Ptger1) plasma membrane (Ptger2, Ptger1) signal transducer activity (Ptger2, Ptger1)
Ptger2 (Mus musculus)
Ptger1 (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 4 93.32 High High
dorsal root ganglion 54 92.64 High High
qutenza 100 91.36 High High
Analgesic 2 91.04 High High
Inflammation 36 87.08 High High
Pain 14 71.04 Quite High
nociceptor 2 62.88 Quite High
substance P 2 61.24 Quite High
cytokine 2 59.84 Quite High
bradykinin 6 58.52 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 46 92.76 High High
Ganglion Cysts 54 91.68 High High
Injury 4 86.40 High High
Nociception 22 82.00 Quite High
Pain 16 71.04 Quite High
Hyperalgesia 36 5.00 Very Low Very Low Very Low
Inflammatory Pain 8 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PGE2 increases TRPV1 activity through EP1 receptors
PGE2 Positive_regulation (increases) of EP1
1) Confidence 0.22 Published 2005 Journal Mol Pain Section Body Doc Link PMC1074353 Disease Relevance 0.09 Pain Relevance 0.62
Prostaglandins act upon a family of pharmacologically distinct prostanoid receptors including EP1, EP2, EP3, EP4 and IP that activate several different G protein-coupled signaling pathways [2,4,5].
EP2 Positive_regulation (activate) of EP1
2) Confidence 0.22 Published 2005 Journal Mol Pain Section Body Doc Link PMC1074353 Disease Relevance 1.31 Pain Relevance 1.02

General Comments

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