INT182565

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.25
First Reported 2005
Last Reported 2005
Negated 0
Speculated 2
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.34
Pain Relevance 1.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Ptger2, Trpv1) cytosol (Trpv1) transport (Trpv1)
signal transduction (Ptger2) transmembrane transport (Trpv1) lipid metabolic process (Trpv1)
Anatomy Link Frequency
PGE2 1
Ptger2 (Mus musculus)
Trpv1 (Mus musculus)
Pain Link Frequency Relevance Heat
IPN 12 97.96 Very High Very High Very High
qutenza 150 96.92 Very High Very High Very High
Inflammation 54 84.24 Quite High
bradykinin 9 84.12 Quite High
Inflammatory mediators 9 83.16 Quite High
Hyperalgesia 9 81.40 Quite High
Pain 21 80.32 Quite High
c fibre 3 71.04 Quite High
unmyelinated 3 70.68 Quite High
withdrawal 15 61.92 Quite High
Disease Link Frequency Relevance Heat
Inflammatory Pain 12 97.96 Very High Very High Very High
INFLAMMATION 69 84.24 Quite High
Hyperalgesia 54 81.40 Quite High
Pain 24 80.32 Quite High
Nociception 33 78.52 Quite High
Ganglion Cysts 81 60.72 Quite High
Injury 6 25.32 Quite Low
Sprains And Strains 9 5.00 Very Low Very Low Very Low
Hypersensitivity 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We next examined the effects of PGE2 on the thermal sensitivity of TRPV1.
PGE2 Spec (examined) Regulation (effects) of TRPV1
1) Confidence 0.25 Published 2005 Journal Mol Pain Section Body Doc Link PMC1074353 Disease Relevance 0.06 Pain Relevance 0.36
Therefore, we examined the effects of PGE2 and PGI2 on TRPV1 activity.
PGE2 Spec (examined) Regulation (effects) of TRPV1
2) Confidence 0.17 Published 2005 Journal Mol Pain Section Body Doc Link PMC1074353 Disease Relevance 0.61 Pain Relevance 0.85
PGE2 or PGI2increased or sensitized TRPV1 responses through EP1 or IP receptors, respectively predominantly in a PKC-dependent manner in both HEK293 cells expressing TRPV1 and mouse DRG neurons.
PGE2 Regulation (responses) of TRPV1 in PGE2
3) Confidence 0.15 Published 2005 Journal Mol Pain Section Abstract Doc Link PMC1074353 Disease Relevance 0.68 Pain Relevance 0.52

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox