INT182634

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Context Info
Confidence 0.39
First Reported 2004
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.29
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CCR5, MIP) endosome (CCR5) transmembrane transport (MIP)
cell-cell signaling (CCR5) cytoplasm (CCR5) signal transducer activity (CCR5)
Anatomy Link Frequency
macrophage 1
CCR5 (Homo sapiens)
MIP (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 24 95.92 Very High Very High Very High
rheumatoid arthritis 1 57.48 Quite High
cytokine 9 35.04 Quite Low
antagonist 32 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
Bioavailability 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 143 100.00 Very High Very High Very High
Infection 36 66.44 Quite High
Bone Cancer 4 65.04 Quite High
Encephalopathy 1 64.04 Quite High
Hepatitis 2 58.48 Quite High
Rheumatoid Arthritis 1 57.48 Quite High
Osteopetrosis 1 55.40 Quite High
Osteoporosis 68 54.68 Quite High
Immunodeficiency 5 50.00 Quite Low
Pox Virus Infection 1 41.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
With the initial discovery that CCR5 was an HIV-1 co-receptor and its endogenous ligands, (MIP-1?
CCR5 Binding (ligands) of MIP associated with acquired immune deficiency syndrome or hiv infection
1) Confidence 0.39 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504054 Disease Relevance 0.51 Pain Relevance 0.11
A CXC chemokine, PBSF/SDF-1, has recently been identified to be a ligand for fusin 60,61 The identification of CCR-5 as the co-receptor for macrophage-tropic viruses is consistent with an earlier report identifying the CCR-5 ligands (RANTES, MIP-1?
CCR-5 Binding (ligands) of MIP in macrophage associated with chemokine
2) Confidence 0.09 Published 2004 Journal International Journal of Medical Sciences Section Body Doc Link PMC1074710 Disease Relevance 0.77 Pain Relevance 0.09

General Comments

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