INT182635

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Context Info
Confidence 0.09
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 7
Disease Relevance 4.19
Pain Relevance 3.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell-cell signaling (CCR5, CCL5) cytoplasm (CCR5, CCL5) endosome (CCR5)
aging (CCL5) signal transducer activity (CCR5) extracellular space (CCL5)
Anatomy Link Frequency
monocytes 2
NK cells 2
memory T cells 2
macrophage 1
CCR5 (Homo sapiens)
CCL5 (Homo sapiens)
Pain Link Frequency Relevance Heat
chemokine 332 99.36 Very High Very High Very High
rheumatoid arthritis 36 94.84 High High
Multiple sclerosis 12 93.60 High High
antagonist 6 66.64 Quite High
Arthritis 18 60.72 Quite High
cytokine 193 50.00 Quite Low
Inflammation 43 5.00 Very Low Very Low Very Low
imagery 25 5.00 Very Low Very Low Very Low
Glutamate receptor 12 5.00 Very Low Very Low Very Low
cerebral cortex 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 71 97.28 Very High Very High Very High
Systemic Lupus Erythematosus 210 95.04 Very High Very High Very High
Rheumatoid Arthritis 36 94.84 High High
Demyelinating Disease 12 93.60 High High
Infection 27 66.44 Quite High
Bone Cancer 4 65.04 Quite High
Arthritis 18 60.72 Quite High
Osteopetrosis 1 55.40 Quite High
Osteoporosis 68 54.68 Quite High
Syndrome 31 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
(RANTES)/CCL5 (a ligand of CCR1, CCR3, and CCR5) is another CC chemokine which attracts monocytes, memory T cells and NK cells and is implicated in the pathophysiology of SLE, rheumatoid arthritis (RA), and multiple sclerosis (MS) [38].
CCR5 Binding (ligand) of RANTES in NK cells associated with chemokine, multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus
1) Confidence 0.09 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896663 Disease Relevance 0.57 Pain Relevance 0.49
(RANTES)/CCL5 (a ligand of CCR1, CCR3, and CCR5) is another CC chemokine which attracts monocytes, memory T cells and NK cells and is implicated in the pathophysiology of SLE, rheumatoid arthritis (RA), and multiple sclerosis (MS) [38].
CCR5 Binding (ligand) of CCL5 in NK cells associated with chemokine, multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus
2) Confidence 0.08 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896663 Disease Relevance 0.57 Pain Relevance 0.49
(RANTES)/CCL5 (a ligand of CCR1, CCR3, and CCR5) is another CC chemokine which attracts monocytes, memory T cells and NK cells and is implicated in the pathophysiology of SLE, rheumatoid arthritis (RA), and multiple sclerosis (MS) [38].
CCR5 Binding (ligand) of RANTES in monocytes associated with chemokine, multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus
3) Confidence 0.03 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896663 Disease Relevance 0.57 Pain Relevance 0.49
(RANTES)/CCL5 (a ligand of CCR1, CCR3, and CCR5) is another CC chemokine which attracts monocytes, memory T cells and NK cells and is implicated in the pathophysiology of SLE, rheumatoid arthritis (RA), and multiple sclerosis (MS) [38].
CCR5 Binding (ligand) of RANTES in memory T cells associated with chemokine, multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus
4) Confidence 0.03 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896663 Disease Relevance 0.57 Pain Relevance 0.49
(RANTES)/CCL5 (a ligand of CCR1, CCR3, and CCR5) is another CC chemokine which attracts monocytes, memory T cells and NK cells and is implicated in the pathophysiology of SLE, rheumatoid arthritis (RA), and multiple sclerosis (MS) [38].
CCR5 Binding (ligand) of CCL5 in monocytes associated with chemokine, multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus
5) Confidence 0.03 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896663 Disease Relevance 0.57 Pain Relevance 0.49
(RANTES)/CCL5 (a ligand of CCR1, CCR3, and CCR5) is another CC chemokine which attracts monocytes, memory T cells and NK cells and is implicated in the pathophysiology of SLE, rheumatoid arthritis (RA), and multiple sclerosis (MS) [38].
CCR5 Binding (ligand) of CCL5 in memory T cells associated with chemokine, multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus
6) Confidence 0.03 Published 2010 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2896663 Disease Relevance 0.57 Pain Relevance 0.49
A CXC chemokine, PBSF/SDF-1, has recently been identified to be a ligand for fusin 60,61 The identification of CCR-5 as the co-receptor for macrophage-tropic viruses is consistent with an earlier report identifying the CCR-5 ligands (RANTES, MIP-1?
CCR-5 Binding (ligands) of RANTES in macrophage associated with chemokine
7) Confidence 0.01 Published 2004 Journal International Journal of Medical Sciences Section Body Doc Link PMC1074710 Disease Relevance 0.77 Pain Relevance 0.09

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