INT182642

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Context Info
Confidence 0.03
First Reported 2004
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.64
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (LTBR)
LTBR (Homo sapiens)
Pain Link Frequency Relevance Heat
Action potential 3 69.76 Quite High
cytokine 7 5.00 Very Low Very Low Very Low
corticosteroid 4 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
Sciatic nerve 3 5.00 Very Low Very Low Very Low
tetrodotoxin 3 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 3 100.00 Very High Very High Very High
Cancer 3 100.00 Very High Very High Very High
Obesity 4 75.00 Quite High
Osteoporosis 69 73.20 Quite High
Immunodeficiency 2 50.00 Quite Low
Osteopetrosis 1 32.96 Quite Low
Bone Cancer 4 13.76 Low Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 71 10.96 Low Low
Infection 15 10.64 Low Low
Disease 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Osteoprotegerin (OPG) is a secreted soluble member of the tumor necrosis factor receptor superfamily (TNFR), also known as osteoclastogenesis inhibitory factor (OCIF) 54,55.
Localization (secreted) of TNFR associated with necrosis and cancer
1) Confidence 0.03 Published 2004 Journal International Journal of Medical Sciences Section Body Doc Link PMC1074710 Disease Relevance 0.51 Pain Relevance 0
The negatively regulated genes included FAS, TNFR, COL6A1, JAM2, FOXQ1, FOXO1, NESTIN, SMAD3, SLIT3, DKK1, WNT5A, BMP1, and GLIS3 which are implicated in differentiation processes as well as a number of novel genes.
Localization (implicated) of TNFR
2) Confidence 0.01 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2747014 Disease Relevance 0.13 Pain Relevance 0.03

General Comments

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