INT182704

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 0.73
Pain Relevance 3.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (NPFF) nucleus (TP53INP2)
Anatomy Link Frequency
parabrachial nucleus 1
NPFF (Homo sapiens)
TP53INP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 336 100.00 Very High Very High Very High
parabrachial 4 99.82 Very High Very High Very High
Opioid 80 98.00 Very High Very High Very High
Analgesic 12 97.76 Very High Very High Very High
narcan 20 97.32 Very High Very High Very High
Brush evoked pain 4 94.48 High High
Periaqueductal grey 4 92.32 High High
Delta opioid receptors 4 89.04 High High
analgesia 28 88.80 High High
withdrawal 4 85.76 High High
Disease Link Frequency Relevance Heat
Neuropathic Pain 8 95.08 Very High Very High Very High
Urological Neuroanatomy 4 92.32 High High
Opiate Addiction 4 86.12 High High
Bordatella Infection 16 80.56 Quite High
Pain 36 72.16 Quite High
Nociception 8 69.68 Quite High
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Neuroblastoma 4 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Inflammatory Pain 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The cell line was used as a model system to learn about the mechanisms involved in the interactions between NPFF and hDOR at the cellular and molecular level.


NPFF Binding (interactions) of hDOR
1) Confidence 0.01 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC1079869 Disease Relevance 0.07 Pain Relevance 0.48
The cell line was used as a model system to learn about the mechanisms involved in the interactions between NPFF and hDOR at the cellular and molecular level.


NPFF Binding (interactions) of hDOR
2) Confidence 0.01 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC1079869 Disease Relevance 0.07 Pain Relevance 0.48
In pontine parabrachial nucleus NPFF modulates synaptic transmission through interaction with presynaptic DOR, providing evidence for the cellular mechanisms of the analgesic action of NPFF at the supraspinal level [12].
NPFF Binding (interaction) of DOR in parabrachial nucleus associated with analgesic and parabrachial
3) Confidence 0.01 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC1079869 Disease Relevance 0.59 Pain Relevance 1.71
In the future, the exact nature of interactions between DOR and NPFF will be further studied.
NPFF Binding (interactions) of DOR associated with opioid receptor
4) Confidence 0.01 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC1079869 Disease Relevance 0 Pain Relevance 0.61

General Comments

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