INT182721

Context Info Confidence 0.26 First Reported 2005 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 7 Total Number 7 Disease Relevance 6.51 Pain Relevance 0.35

SHE (Homo sapiens)

Pain Link Frequency Relevance Heat alcohol 34 98.68 Inflammation 3 98.28 Arthritis 6 90.40 Pain 17 71.36 tolerance 5 58.32 addiction 20 54.28 Angina 3 48.80 depression 21 5.00 Analgesic 7 5.00 methadone 5 5.00

Disease Link Frequency Relevance Heat Systemic Lupus Erythematosus 108 100.00 Pharyngitis 6 99.08 INFLAMMATION 3 98.28 Pneumonia 5 98.24 Infection 32 97.52 Mental Disorders 116 96.88 Arthralgia 12 92.32 Acquired Immune Deficiency Syndrome Or Hiv Infection 133 92.24 Fever 23 91.76 Appetite Loss 4 91.12

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

She was not depressed: ‘Now I am off the two of them (alcohol and heroin) I am happy as a lark’ and ‘I feel better now than when I was younger’.

Neg (not) Negative_regulation (depressed) of She associated with alcohol

1) Confidence 0.26 Published 2010 Journal Journal of Advanced Nursing Section Body Doc Link PMC2984546 Disease Relevance 0.17 Pain Relevance 0.05

If she is educated and employed she makes her own decisions.

Negative_regulation (employed) of she

2) Confidence 0.17 Published 2007 Journal BMC Public Health Section Body Doc Link PMC2222163 Disease Relevance 0.33 Pain Relevance 0.03

Inf.3, 5 and 7 almost at the same time: Its the mother Inf.4: The very mother of a child, is she not the very one who can tell the father?

Negative_regulation (is) of she

3) Confidence 0.11 Published 2005 Journal BMC Public Health Section Body Doc Link PMC1079879 Disease Relevance 0.16 Pain Relevance 0

She felt she was pushed aside as a child because her brothers always came first.

Negative_regulation (pushed) of she

4) Confidence 0.11 Published 2008 Journal Subst Abuse Treat Prev Policy Section Body Doc Link PMC2612649 Disease Relevance 0.54 Pain Relevance 0.03

She then discontinued her anti-lupus medications and was lost to follow-up.

Negative_regulation (lost) of She associated with systemic lupus erythematosus

5) Confidence 0.05 Published 2008 Journal Pediatr Rheumatol Online J Section Abstract Doc Link PMC2390549 Disease Relevance 1.34 Pain Relevance 0.05

She was then lost to follow-up for 13 months and did not take her medications.

Negative_regulation (lost) of She

6) Confidence 0.05 Published 2008 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2390549 Disease Relevance 1.20 Pain Relevance 0.05

After being lost to follow-up and discontinuing her medications, she presented with fungal pharyngitis and then pneumonia and MAC infection.

Negative_regulation (lost) of she associated with pharyngitis, pneumonia and infection

7) Confidence 0.05 Published 2008 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2390549 Disease Relevance 2.78 Pain Relevance 0.14

General Comments

This test has worked.