INT182754

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Context Info
Confidence 0.67
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 4.50
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
beta cell 1
T2DM (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 2 53.28 Quite High
Inflammation 30 5.00 Very Low Very Low Very Low
Pain 16 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
Tetrahydrobiopterin 6 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
Osteoarthritis 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 106 100.00 Very High Very High Very High
Insulin Resistance 12 100.00 Very High Very High Very High
Prediabetic State 4 100.00 Very High Very High Very High
Alzheimer's Dementia 2 99.04 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

2 97.88 Very High Very High Very High
Hyperlipidemia 4 97.28 Very High Very High Very High
Disorder Of Lipid Metabolism 6 96.88 Very High Very High Very High
Calcification 196 90.72 High High
Intellectual Impairment 2 90.60 High High
Hypertrophy 4 89.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to insulin and IGF-1, there is another beta cell derived islet hormone that is elevated in IR, metS, prediabetes, and early T2DM termed amylin or islet amyloid polypeptide.
Positive_regulation (elevated) of T2DM in beta cell associated with diabetes mellitus, alzheimer's dementia, prediabetic state and insulin resistance
1) Confidence 0.67 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC1079905 Disease Relevance 2.62 Pain Relevance 0
The lipid triad of the metS and T2DM consists of an elevation in VLDL-C or triglycerides, small dense atherogenic LDL-C, and a decrease in HDL-C.
Positive_regulation (elevation) of T2DM associated with diabetes mellitus and disorder of lipid metabolism
2) Confidence 0.45 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC1079905 Disease Relevance 1.78 Pain Relevance 0.03

General Comments

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