INT182788

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Context Info
Confidence 0.40
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 11.33
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ETV3) molecular_function (ETV3) biological_process (ETV3)
ETV3 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 4 95.64 Very High Very High Very High
cytokine 32 92.88 High High
Inflammation 72 92.48 High High
withdrawal 2 71.72 Quite High
ischemia 8 70.96 Quite High
Pain 35 57.28 Quite High
Tetrahydrobiopterin 12 5.00 Very Low Very Low Very Low
imagery 9 5.00 Very Low Very Low Very Low
Osteoarthritis 8 5.00 Very Low Very Low Very Low
Angina 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 240 100.00 Very High Very High Very High
Chronic Renal Failure 180 100.00 Very High Very High Very High
Metabolic Syndrome 139 100.00 Very High Very High Very High
Cv Unclassified Under Development 100 100.00 Very High Very High Very High
Syndrome 62 100.00 Very High Very High Very High
Insulin Resistance 48 100.00 Very High Very High Very High
Prediabetic State 8 99.92 Very High Very High Very High
Stress 26 99.86 Very High Very High Very High
Calciphylaxis 164 99.84 Very High Very High Very High
Abdominal Obesity 6 99.76 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, little is known about the intracellular molecular mechanisms present in MetS.
Gene_expression (present) of MetS associated with metabolic syndrome
1) Confidence 0.40 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2940873 Disease Relevance 1.45 Pain Relevance 0.15
Therefore, IS of insulin seems to be impaired at least at the IRS-1 level in MetS.
Gene_expression (level) of MetS associated with metabolic syndrome
2) Confidence 0.40 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2940873 Disease Relevance 0.64 Pain Relevance 0.04
The authors suggest that the introduction of METs has been driven not by evidence of efficacy but by evidence of suboptimal care of acutely ill patients in hospital and an assumption that pre-emptive intensive care would either save lives or permit a dignified death.
Gene_expression (introduction) of METs associated with death
3) Confidence 0.30 Published 2008 Journal Crit Care Section Body Doc Link PMC2481455 Disease Relevance 0.38 Pain Relevance 0
With the introduction of the MetS, the abdominal obesity was recognized as a clinically measurable (although imperfect) entity [8,16-18].
Gene_expression (introduction) of MetS associated with abdominal obesity and metabolic syndrome
4) Confidence 0.25 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2949857 Disease Relevance 1.68 Pain Relevance 0
With the current epidemic of obesity, metS, insulin resistance related T2DM (diabesity) in all age groups and particularly the aged and adolescent youth, a closer examination of this morbid – mortal complication is in order [83-87].
Gene_expression (resistance) of metS associated with diabetes mellitus, metabolic syndrome and insulin resistance
5) Confidence 0.17 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC1079905 Disease Relevance 2.36 Pain Relevance 0.05
This review has been an attempt to increase our basic understanding of VOC and its mechanisms in the patient with metS, T2DM, CKD, CHD, and the syndrome of CPLX.
Gene_expression (syndrome) of metS associated with calciphylaxis, calcification, chronic renal failure, syndrome, diabetes mellitus and cv unclassified under development
6) Confidence 0.17 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC1079905 Disease Relevance 1.89 Pain Relevance 0
There are multiple causes for eNOS enzyme uncoupling: The A-FLIGHT -U multiple metabolic toxicities, oxidative – redox stress, ROS, metS, insulin resistance, prediabetes, T2DM and T1DM, Htn, endothelin, and asymmetrical dimethyl arginine (ADMA) [1,19,20,27,28,34,45].
Gene_expression (resistance) of metS associated with stress, diabetes mellitus, cv unclassified under development, prediabetic state and insulin resistance
7) Confidence 0.17 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC1079905 Disease Relevance 1.07 Pain Relevance 0.13
Insulin, IGF-1, and amylin are known to be elevated in the insulin resistance (IR) and metS patient [21].
Gene_expression (patient) of metS associated with insulin resistance
8) Confidence 0.14 Published 2005 Journal Cardiovasc Diabetol Section Body Doc Link PMC1079905 Disease Relevance 1.85 Pain Relevance 0

General Comments

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