INT182837

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Context Info
Confidence 0.12
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.57
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Creb1, Crebbp) DNA binding (Creb1, Crebbp) transcription factor binding (Creb1, Crebbp)
cell proliferation (Crebbp) mitochondrion (Creb1) protein complex (Crebbp)
Creb1 (Mus musculus)
Crebbp (Mus musculus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 2 91.28 High High
Morphine 1 87.36 High High
Pain 10 72.56 Quite High
amygdala 1 40.80 Quite Low
qutenza 37 5.00 Very Low Very Low Very Low
Eae 10 5.00 Very Low Very Low Very Low
Lasting pain 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 2 88.80 High High
Appetite Loss 1 77.60 Quite High
Anxiety Disorder 56 75.96 Quite High
Pain 10 72.56 Quite High
Targeted Disruption 8 58.80 Quite High
Injury 1 50.00 Quite Low
Shock 16 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Phosphorylated CREB recruits the transcriptional co-activator CBP (CREB binding protein) which leads to the activation of CRE (cAMP response element) containing promoters and ultimately to gene expression [9-11].
CREB Binding (recruits) of CBP
1) Confidence 0.12 Published 2005 Journal Mol Pain Section Body Doc Link PMC1079936 Disease Relevance 0.57 Pain Relevance 0.32

General Comments

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