INT182952

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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.45
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (KCNIP3, HNF4A) cytoplasm (KCNIP3, HNF4A) nucleus (KCNIP3, HNF4A)
cell differentiation (HNF4A) nucleoplasm (HNF4A) Golgi apparatus (KCNIP3)
KCNIP3 (Homo sapiens)
HNF4A (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 60 100.00 Very High Very High Very High
Neuroblastoma 18 80.48 Quite High
Apoptosis 3 65.52 Quite High
Repression 12 18.96 Low Low
Pain 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DREAM activates RARE-dependent transcription
DREAM Positive_regulation (activates) of transcription
1) Confidence 0.02 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0.20 Pain Relevance 0
Thus, DREAM can cooperate with vitamin D and RA to increase HRE-dependent transcription without a direct interaction with their receptors.
DREAM Positive_regulation (increase) of transcription associated with rheumatoid arthritis
2) Confidence 0.02 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0.10 Pain Relevance 0
Nevertheless, stimulation of HRE-mediated transcription by DREAM and the nuclear receptors appears to have distinct requirements.
DREAM Positive_regulation (mediated) of transcription
3) Confidence 0.02 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0.15 Pain Relevance 0

General Comments

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