INT182977

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.49
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.34
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (PELP1) cytoplasm (PELP1)
PELP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 18 75.84 Quite High
agonist 22 20.60 Low Low
anesthesia 3 5.00 Very Low Very Low Very Low
Dopamine 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Clonidine 2 5.00 Very Low Very Low Very Low
Eae 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
dopamine receptor 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 5 94.04 High High
Stress 1 89.04 High High
Shock 2 77.20 Quite High
Impaired Glucose Tolerance 18 76.48 Quite High
Breast Cancer 3 43.48 Quite Low
Obesity 30 35.04 Quite Low
Cancer 3 13.56 Low Low
Apoptosis 5 10.44 Low Low
Rheumatoid Arthritis 21 5.00 Very Low Very Low Very Low
Body Weight 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
is a result of p160 coactivator interaction with ER?
Positive_regulation (result) of p160
1) Confidence 0.49 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2432036 Disease Relevance 0.17 Pain Relevance 0.04
This appears to be the case, because reduced recruitment of p160 coactivators by the RXR/VDR heterodimer bound to the DRE was found.
Positive_regulation (coactivators) of p160
2) Confidence 0.18 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0 Pain Relevance 0
Rho activation occurs primarily via activation of Rho exchange factors by G proteins of the G12 subfamily, and leads to activation of p160 ROCK which mediates morphological changes by altering cytoskeletal structure.
Positive_regulation (activation) of p160
3) Confidence 0.18 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2621239 Disease Relevance 0.17 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox