INT183009

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Context Info
Confidence 0.68
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.00
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (VDR) signal transduction (VDR) cell morphogenesis (VDR)
nucleus (VDR) DNA binding (VDR)
Anatomy Link Frequency
muscle cells 1
liver 1
VDR (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 4 95.76 Very High Very High Very High
Calcium channel 1 83.60 Quite High
Pain 48 77.00 Quite High
Central nervous system 12 53.40 Quite High
Inflammation 7 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Dopamine 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 11 95.40 Very High Very High Very High
Hypertrophy 3 82.84 Quite High
Pain 35 77.00 Quite High
Myalgia 13 73.00 Quite High
Rickets 4 54.76 Quite High
Muscle Weakness 9 50.00 Quite Low
Hip Fractures 2 42.56 Quite Low
Muscle Disease 8 31.36 Quite Low
Apoptosis 3 25.68 Quite Low
Rheumatoid Arthritis 20 12.88 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Expression vectors for VDR and RAR?
Phosphorylation (vectors) of VDR
1) Confidence 0.68 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0 Pain Relevance 0
Furthermore, the active form of vitamin D, 1,25(OH)2D, influences the differentiation and proliferation of muscle cells [5].
Phosphorylation (form) of vitamin D in muscle cells
2) Confidence 0.55 Published 2010 Journal Journal of Nutrition and Metabolism Section Body Doc Link PMC3010688 Disease Relevance 1.00 Pain Relevance 0.61
In the liver, cholecalciferol is transformed into calcifediol or 25(OH)D, which enters the blood circulation, then, in the renal tubular cells, calcifediol is hydroxylated into calcitriol or 1,25-dihydroxyvitamin D (1,25(OH)D) which is the active form of vitamin D [38,40].
Phosphorylation (form) of vitamin D in liver
3) Confidence 0.31 Published 2010 Journal J Neuroeng Rehabil Section Body Doc Link PMC2959005 Disease Relevance 0 Pain Relevance 0.07

General Comments

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