INT183014

Context Info Confidence 0.00 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.06 Pain Relevance 0

nucleoplasm (NR1H4) signal transduction (NR1H4) nucleus (NR1H4)

NR1H4 (Homo sapiens) Dre (Mus musculus)

Pain Link Frequency Relevance Heat antagonist 4 5.00 Pain 2 5.00

Disease Link Frequency Relevance Heat Rheumatoid Arthritis 40 63.28 Neuroblastoma 12 5.00 Repression 8 5.00 Pain 2 5.00 Apoptosis 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Conversely, binding of the receptor heterodimer VDR/RXR to the DRE was also observed, although with a lower affinity than to the VDRE (Figure 1A, lanes 2 versus lane 5).

RXR Binding (binding) of DRE

1) Confidence 0.00 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0.06 Pain Relevance 0

This appears to be the case, because reduced recruitment of p160 coactivators by the RXR/VDR heterodimer bound to the DRE was found.

RXR Binding (bound) of DRE

2) Confidence 0.00 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1084319 Disease Relevance 0 Pain Relevance 0

General Comments

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