INT183060

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Context Info
Confidence 0.44
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.34
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (INS) small molecule metabolic process (INS) extracellular region (INS)
carbohydrate metabolic process (INS) cell-cell signaling (INS)
INS (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 5.00 Very Low Very Low Very Low
Paracetamol 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Somatostatin 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperinsulinism 3 100.00 Very High Very High Very High
Apoptosis 5 79.80 Quite High
Hyperglycemia 1 39.88 Quite Low
Alzheimer's Dementia 1 33.76 Quite Low
Rheumatoid Arthritis 17 19.68 Low Low
Diabetes Mellitus 9 5.00 Very Low Very Low Very Low
Stress 7 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Leukemia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Coinciding with the onset of high insulin expression levels in mouse islets, ngn3 expression is virtually extinguished [25], while expression of Pdx1, FoxA3, Isl1, and Nkx6.1 in islet ?
Regulation (onset) of Transcription (levels) of insulin associated with hyperinsulinism
1) Confidence 0.44 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1087208 Disease Relevance 0.34 Pain Relevance 0
However, there was no significant change in proinsulin, Ucp-2 or Gck mRNA expression following 24-h stimulation with AA.
Neg (no) Regulation (change) of Transcription (expression) of proinsulin
2) Confidence 0.44 Published 2010 Journal Clinical Science (London, England : 1979) Section Body Doc Link PMC2990202 Disease Relevance 0 Pain Relevance 0

General Comments

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