INT183161

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Context Info
Confidence 0.05
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.50
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pde2a) signal transduction (Pde2a) Golgi apparatus (Pde2a)
endoplasmic reticulum (Pde2a) plasma membrane (Pde2a) nucleus (Pde2a)
Anatomy Link Frequency
granulocytes 1
Pde2a (Mus musculus)
Pain Link Frequency Relevance Heat
Eae 6 96.72 Very High Very High Very High
agonist 21 95.84 Very High Very High Very High
Spinal cord 29 94.08 High High
qutenza 1 84.44 Quite High
Inflammatory stimuli 2 80.80 Quite High
Pain 11 69.68 Quite High
Inflammation 64 50.00 Quite Low
Morphine 16 14.88 Low Low
adenocard 36 5.00 Very Low Very Low Very Low
allodynia 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Inflammatory Pain 4 96.72 Very High Very High Very High
INFLAMMATION 54 80.44 Quite High
Pain 13 69.68 Quite High
Neuropathic Pain 11 66.72 Quite High
Nociception 25 52.80 Quite High
Sprains And Strains 5 38.12 Quite Low
Lung Injury 35 17.92 Low Low
Adhesions 3 16.40 Low Low
Edema 3 11.40 Low Low
Injury 7 5.72 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The presumed target of cGMP is cGMP dependent protein kinase (PKG).
Regulation (target) of cGMP
1) Confidence 0.05 Published 2005 Journal Mol Pain Section Body Doc Link PMC1310513 Disease Relevance 0.50 Pain Relevance 0.62
When pharmacologic effects of CGS21680 were tested on BAL granulocytes, no LPS was added.
Regulation (effects) of CGS21680 in granulocytes
2) Confidence 0.00 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1088279 Disease Relevance 0 Pain Relevance 0.05

General Comments

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