INT183205

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Context Info
Confidence 0.11
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 1.33
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (UTS2R) plasma membrane (UTS2R) signal transducer activity (UTS2R)
UTS2R (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 4 97.88 Very High Very High Very High
adenocard 2 14.36 Low Low
Inflammation 10 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Chronic pancreatitis 3 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
aspirin 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 378 97.00 Very High Very High Very High
Colon Cancer 13 83.28 Quite High
Apoptosis 66 77.80 Quite High
Carcinoma 12 73.56 Quite High
Breast Cancer 13 63.08 Quite High
Disease 9 58.24 Quite High
Glioblastoma 9 41.60 Quite Low
Helminth Infection 3 39.00 Quite Low
Chronic Lymphoid Leukemia 21 5.00 Very Low Very Low Very Low
Prostate Cancer 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-UTR of COX-2 is complex and has many AREs (Figure 1).
UTR Binding (complex) of
1) Confidence 0.11 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1088970 Disease Relevance 0 Pain Relevance 0.05
-UTR is larger than average, encompassing ?
UTR Binding (average) of
2) Confidence 0.11 Published 2005 Journal Nucleic Acids Research Section Body Doc Link PMC1088970 Disease Relevance 0 Pain Relevance 0
They accomplish this by binding to the 3’ untranslated region (3’UTR) of target messengerRNA (mRNA), resulting in either their degradation or inhibition of translation, depending on the degree of complementary base pairing.
UTR Binding (binding) of
3) Confidence 0.07 Published 2008 Journal Current Genomics Section Abstract Doc Link PMC2674802 Disease Relevance 0.28 Pain Relevance 0
They screened the 3’UTR of Pdcd4 in search of any complementarity to the seed sequences of known miRNAs and found an exact match target sequence for miR-21.
UTR Binding (screened) of
4) Confidence 0.05 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674802 Disease Relevance 1.06 Pain Relevance 0
The miRNAs play a role in post-transcriptional regulation by binding to the 3’ untranslated region (3’UTR) of target messengerRNA (mRNA).
UTR Binding (binding) of
5) Confidence 0.05 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674802 Disease Relevance 0 Pain Relevance 0

General Comments

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