INT183374

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.30
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 5.03
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Dntt) intracellular (Dntt) DNA binding (Dntt)
nucleotidyltransferase activity (Dntt) DNA metabolic process (Dntt) cytoplasm (Dntt)
Anatomy Link Frequency
apoptotic cells 2
extracellular matrix 1
Dntt (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 21 87.24 High High
Multiple sclerosis 9 85.64 High High
Central nervous system 7 84.68 Quite High
Demyelination 37 79.56 Quite High
Nerve growth factor 4 78.40 Quite High
alcohol 55 65.64 Quite High
cytokine 7 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 106 97.96 Very High Very High Very High
Death 16 95.20 Very High Very High Very High
Multiple Sclerosis 5 90.64 High High
Experimental Autoimmune Encephalomyelitis 2 90.44 High High
Necrosis 17 88.48 High High
INFLAMMATION 23 87.24 High High
Demyelinating Disease 55 85.64 High High
Cancer 2 81.76 Quite High
Disease 17 77.00 Quite High
Aseptic Necrosis Of Bone 150 62.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The TUNEL method used in this study is based on the specific binding of the terminal deoxynucleotidyl transferase (TdT) to 3-OH (3-hydroxyl) ends of fragmented DNA from apoptotic cells, yielding polydeoxylnucleotide polymers.10) The TUNEL method makes it possible for direct observations and quantification of the fraction of cells undergoing apoptosis without damaging the tissue architecture.
TdT Binding (binding) of in apoptotic cells associated with apoptosis
1) Confidence 0.30 Published 2010 Journal Clinics in Orthopedic Surgery Section Body Doc Link PMC2981783 Disease Relevance 1.50 Pain Relevance 0.17
Moreover, steric hindrance, which can be caused by extracellular matrix components, can prevent the access of TdT to DNA strand breaks.
TdT Binding (access) of in extracellular matrix
2) Confidence 0.27 Published 2010 Journal Clinics in Orthopedic Surgery Section Body Doc Link PMC2981783 Disease Relevance 1.15 Pain Relevance 0.07
The TUNEL method used in this study is based on the specific binding of the terminal deoxynucleotidyl transferase (TdT) to 3-OH (3-hydroxyl) ends of fragmented DNA from apoptotic cells, yielding polydeoxylnucleotide polymers.10) The TUNEL method makes it possible for direct observations and quantification of the fraction of cells undergoing apoptosis without damaging the tissue architecture.
deoxynucleotidyl transferase Binding (binding) of in apoptotic cells associated with apoptosis
3) Confidence 0.26 Published 2010 Journal Clinics in Orthopedic Surgery Section Body Doc Link PMC2981783 Disease Relevance 1.45 Pain Relevance 0.17
terminal deoxynucleotidyltransferase (TdT)-mediated dUTP nick end labeling (TUNEL)
terminal deoxynucleotidyltransferase Binding (labeling) of
4) Confidence 0.07 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC1112612 Disease Relevance 0.93 Pain Relevance 0.39

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox