INT183375

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Context Info
Confidence 0.38
First Reported 2005
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 14
Total Number 15
Disease Relevance 8.95
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nppa) cytoplasm (Nppa)
Anatomy Link Frequency
heart 2
body 2
eyes 1
incisor 1
central nervous system 1
Nppa (Mus musculus)
Pain Link Frequency Relevance Heat
Demyelination 74 99.92 Very High Very High Very High
Central nervous system 14 99.56 Very High Very High Very High
Multiple sclerosis 18 75.76 Quite High
Inflammation 36 75.64 Quite High
Eae 64 66.64 Quite High
agonist 4 53.32 Quite High
cytokine 15 53.20 Quite High
alcohol 2 16.60 Low Low
midbrain 2 15.28 Low Low
anesthesia 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 756 100.00 Very High Very High Very High
Demyelinating Disease 110 99.92 Very High Very High Very High
Weight Gain 10 99.42 Very High Very High Very High
Body Weight 132 98.82 Very High Very High Very High
Myocardial Infarction 86 98.76 Very High Very High Very High
Death 29 98.12 Very High Very High Very High
Coronary Heart Disease 32 96.96 Very High Very High Very High
Paralysis 4 96.96 Very High Very High Very High
Weight Loss 4 94.84 High High
Natriuresis 22 93.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
BTBR pups were able to right themselves as early as pnd 2 [strain×age interaction: F(6,108)?
pnd Binding (interaction) of associated with sprains and strains
1) Confidence 0.38 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516927 Disease Relevance 0.49 Pain Relevance 0
However, these studies could not distinguish between systemic and cardiac interactions of ANP/BNP and Ang II.
ANP Binding (interactions) of
2) Confidence 0.36 Published 2010 Journal Basic Res Cardiol Section Body Doc Link PMC2916114 Disease Relevance 0.18 Pain Relevance 0.03
BTBR and FVB/NJ pups had significantly greater weight gains starting from pnd 4 through pnd 12 [strain×age interaction: F(12,144)?
pnd Binding (interaction) of associated with sprains and strains and weight gain
3) Confidence 0.29 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516927 Disease Relevance 1.06 Pain Relevance 0
Post hoc comparisons revealed that BTBR pups showed faster incisor growth between pnd 6 and 12 [strain×age interaction: F(4,72)?
pnd Binding (interaction) of in incisor associated with sprains and strains
4) Confidence 0.29 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516927 Disease Relevance 0.55 Pain Relevance 0
BTBR pups showed a greater response to an acoustic stimulus, as shown by the auditory startle measurements on pnd 12 [strain×age interaction: F(3,54)?
pnd Binding (interaction) of associated with sprains and strains
5) Confidence 0.29 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516927 Disease Relevance 0.47 Pain Relevance 0.09
BTBR and B6 pups acquired the negative geotaxis response at different rates, with BTBR showing lower latencies starting at pnd 4 [strain×age interaction: F(6,108)?
pnd Binding (interaction) of associated with sprains and strains
6) Confidence 0.29 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516927 Disease Relevance 0.52 Pain Relevance 0
Replicating the body weight difference seen in Cohort 1, BTBR mice were significantly heavier than B6 on pnd 4, 6, 8, and 12 [strain×age interaction: F(6,108)?
pnd Binding (heavier) of in body associated with body weight and sprains and strains
7) Confidence 0.29 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516927 Disease Relevance 1.24 Pain Relevance 0
Replicating the body weight difference seen in Cohort 1, BTBR mice were significantly heavier than B6 on pnd 4, 6, 8, and 12 [strain×age interaction: F(6,108)?
pnd Binding (interaction) of in body associated with body weight and sprains and strains
8) Confidence 0.29 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516927 Disease Relevance 1.24 Pain Relevance 0
At pnd 12, B6 animals still had their eyes closed, while BTBR pups had eyes partially open [strain×age interaction: F(3,54)?
pnd Binding (had) of in eyes associated with sprains and strains
9) Confidence 0.29 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2516927 Disease Relevance 0.53 Pain Relevance 0
To elucidate whether these selective interactions between ANP and Ang II, but not ISO signalling play a role in vivo, in intact hearts, we compared the cardiac hypertrophic responses of CM GC-A KO and respective control littermates [18] to exogenous Ang II or ISO administration.
ANP Neg (not) Binding (interactions) of in hearts
10) Confidence 0.28 Published 2010 Journal Basic Res Cardiol Section Body Doc Link PMC2916114 Disease Relevance 0.10 Pain Relevance 0
However, we find precisely maintained PR intervals with no sex difference present through PND28.
PND28 Neg (no) Binding (find) of
11) Confidence 0.15 Published 2010 Journal BMC Physiol Section Body Doc Link PMC2936334 Disease Relevance 0.21 Pain Relevance 0
Average heart rates were observed to rise steadily in developing neonates at a rate of approximately 25 bpm per day, from ~425 bpm at PND2 to ~725 bpm on PND14.
PND14 Binding (~725) of in heart
12) Confidence 0.15 Published 2010 Journal BMC Physiol Section Body Doc Link PMC2936334 Disease Relevance 0.05 Pain Relevance 0
-immunoreactive cells were not recognized at PND 20 (Fig. 1C) in twi/twi.
PND Binding (recognized) of
13) Confidence 0.12 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC1112612 Disease Relevance 0.16 Pain Relevance 0.05
Obvious demyelination is recognized after PND 30 in the central nervous system (CNS).
PND Binding (recognized) of in central nervous system associated with demyelination and central nervous system
14) Confidence 0.12 Published 2005 Journal J Neuroinflammation Section Body Doc Link PMC1112612 Disease Relevance 1.36 Pain Relevance 0.35
N-ANP has been demonstrated to be associated with late mortality following AMI [41].
N-ANP Binding (associated) of associated with myocardial infarction
15) Confidence 0.04 Published 2010 Journal BMC Med Section Body Doc Link PMC2898678 Disease Relevance 0.79 Pain Relevance 0

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