INT183389

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Context Info
Confidence 0.01
First Reported 2004
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 5.17
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Apob) transport (Apob) extracellular space (Apob)
extracellular region (Apob) endoplasmic reticulum (Apob) enzyme binding (Apob)
Apob (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 1 98.20 Very High Very High Very High
headache 1 36.00 Quite Low
Dismenorea 6 20.52 Low Low
cva 40 5.00 Very Low Very Low Very Low
Pain 23 5.00 Very Low Very Low Very Low
withdrawal 6 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
carpal tunnel syndrome 4 5.00 Very Low Very Low Very Low
Osteoarthritis 4 5.00 Very Low Very Low Very Low
Paresthesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 134 100.00 Very High Very High Very High
Vasculitis 1 98.20 Very High Very High Very High
Advanced Or Metastatic Breast Cancer 28 97.76 Very High Very High Very High
Increased Venous Pressure Under Development 8 95.88 Very High Very High Very High
Diabetes Mellitus 51 94.96 High High
Breast Cancer 50 94.64 High High
Hyperlipidemia 20 86.72 High High
Coronary Artery Disease 5 74.04 Quite High
Myocardial Infarction 26 67.12 Quite High
Coronary Heart Disease 28 61.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The importance of changes in apolipoprotein B and non-HDL-cholesterol levels appears greater with fibrate therapy than with statin use [36], particularly in patients with type 2 diabetes [37].
Regulation (changes) of apolipoprotein B associated with diabetes mellitus and disorder of lipid metabolism
1) Confidence 0.01 Published 2004 Journal Cardiovasc Diabetol Section Body Doc Link PMC1129022 Disease Relevance 1.25 Pain Relevance 0.05
There was no significant difference in change of apolipoprotein B level between the two groups (-1.99 +/- 2.3%, p = 0.392).


Regulation (change) of apolipoprotein B associated with disorder of lipid metabolism
2) Confidence 0.01 Published 2009 Journal Lipids Health Dis Section Body Doc Link PMC2803170 Disease Relevance 0.58 Pain Relevance 0
In contrast, a substudy of an advanced breast cancer phase II randomized trial did not find the treatment with either exemestane or tamoxifen to have a significant effect on total cholesterol, HDL-C, apolipoprotein A1, or apolipoprotein B.
Regulation (effect) of apolipoprotein B associated with advanced or metastatic breast cancer and disorder of lipid metabolism
3) Confidence 0.00 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2503653 Disease Relevance 1.47 Pain Relevance 0
Anastrozole induced no significant change of serum levels of apolipoprotein A1, apolipoprotein B, triglycerides, total cholesterol, HDL-C, and LDL-C.
Neg (no) Regulation (change) of apolipoprotein B associated with disorder of lipid metabolism
4) Confidence 0.00 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2503653 Disease Relevance 1.80 Pain Relevance 0

General Comments

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