INT183631

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Context Info
Confidence 0.13
First Reported 2005
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 5.64
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Macf1) ATPase activity (Macf1) plasma membrane (Macf1)
cytoskeleton (Macf1) cytoplasm (Macf1)
Anatomy Link Frequency
colon 1
Macf1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 14 94.08 High High
cINOD 8 60.84 Quite High
COX-2 inhibitor 5 50.00 Quite Low
anesthesia 3 43.08 Quite Low
Bile 1 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aberrant Crypt Foci 133 100.00 Very High Very High Very High
Targeted Disruption 240 99.88 Very High Very High Very High
Cancer 299 99.28 Very High Very High Very High
INFLAMMATION 11 94.08 High High
Colon Cancer 143 81.68 Quite High
Adenoma 112 77.08 Quite High
Inflammatory Bowel Disease 25 76.04 Quite High
Colitis 17 71.44 Quite High
Dislocations 6 64.48 Quite High
Death 2 41.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, at an early stage of tumor development IGF-II transgenic mice displayed predominantly more ACF containing ?
Gene_expression (displayed) of ACF associated with aberrant crypt foci, targeted disruption and cancer
1) Confidence 0.13 Published 2006 Journal J Carcinog Section Body Doc Link PMC1660565 Disease Relevance 1.99 Pain Relevance 0
Interestingly, at an early stage of tumor development IGF-II transgenic mice displayed predominantly more ACF containing ?
Gene_expression (containing) of ACF associated with aberrant crypt foci, targeted disruption and cancer
2) Confidence 0.13 Published 2006 Journal J Carcinog Section Body Doc Link PMC1660565 Disease Relevance 2.03 Pain Relevance 0
The colon was fixed and stained for ACF and microadenomas as described before.
Gene_expression (fixed) of ACF in colon associated with aberrant crypt foci
3) Confidence 0.13 Published 2006 Journal J Carcinog Section Body Doc Link PMC1660565 Disease Relevance 0.86 Pain Relevance 0
In addition, Rao et al. [48] showed that an iNOS-selective inhibitor suppresses AOM-induced colonic ACF development and iNOS activity.
Gene_expression (development) of ACF associated with aberrant crypt foci
4) Confidence 0.07 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1156872 Disease Relevance 0.77 Pain Relevance 0.18

General Comments

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