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Context Info
Confidence 0.07
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.05
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Lef1, Ctnnd2) cell adhesion (Ctnnd2) histone binding (Lef1)
DNA binding (Lef1) transcription factor binding (Lef1) cytoplasm (Lef1)
Anatomy Link Frequency
nucleus 1
Lef1 (Mus musculus)
Ctnnd2 (Mus musculus)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 5 50.00 Quite Low
Inflammation 14 17.08 Low Low
cINOD 8 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 2 96.32 Very High Very High Very High
Apoptosis 14 88.88 High High
Cancer 14 71.80 Quite High
Colon Cancer 20 65.76 Quite High
Hyperplasia 3 62.84 Quite High
Death 2 52.92 Quite High
Colitis 17 50.00 Quite Low
Adenocarcinoma 20 46.96 Quite Low
Aberrant Crypt Foci 7 23.12 Low Low
INFLAMMATION 11 17.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin interacts with T-cell factor (Tcf) or lymphoid-enhancer factor (Lef) and translocates to the nucleus, in which it transactivates target genes including c-myc and cyclin D1 that are the potentially oncogenic [47,60] in the cytoplasm or nucleus as a consequence of mutant Apc or ?
Lef Binding (interacts) of catenin in nucleus
1) Confidence 0.07 Published 2005 Journal BMC Cancer Section Body Doc Link PMC1156872 Disease Relevance 1.05 Pain Relevance 0

General Comments

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