INT183668

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Context Info
Confidence 0.36
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 15
Total Number 15
Disease Relevance 9.86
Pain Relevance 2.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (SGCA) cytoplasm (SGCA)
SGCA (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 110 100.00 Very High Very High Very High
Pain 125 99.80 Very High Very High Very High
Lasting pain 2 99.58 Very High Very High Very High
addiction 9 97.76 Very High Very High Very High
Arthritis 6 91.80 High High
antidepressant 5 77.76 Quite High
Osteoarthritis 101 76.00 Quite High
antagonist 10 70.60 Quite High
nMDA receptor 14 69.84 Quite High
Glutamate 25 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 141 100.00 Very High Very High Very High
Dyspnea 100 100.00 Very High Very High Very High
Cognitive Disorder 97 100.00 Very High Very High Very High
Vomiting 12 99.90 Very High Very High Very High
Pain 124 99.80 Very High Very High Very High
Appetite Loss 6 99.48 Very High Very High Very High
Pressure And Volume Under Development 5 99.28 Very High Very High Very High
Stroke 289 99.22 Very High Very High Very High
Disease 342 98.92 Very High Very High Very High
Chronic Disease 19 97.56 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Behavioral factors and particularly comorbidities were largely responsible for the social class differences, especially for ADL disability but also to some extent for IADL disability and functional limitations.
ADL Binding (disability) of
1) Confidence 0.36 Published 2008 Journal Ann Epidemiol Section Body Doc Link PMC2728204 Disease Relevance 0.60 Pain Relevance 0.05
The correlation between KOOS Pain and SF-36 BP, between KOOS Pain and SF-36 PF, KOOS (all subscales) and VAS for Pain and KOOS ADL and SF-36 PF should be ?
ADL Binding (be) of associated with pain
2) Confidence 0.36 Published 2008 Journal Health Qual Life Outcomes Section Body Doc Link PMC2289810 Disease Relevance 0.79 Pain Relevance 0.79
Presence of local swelling, anorexia, nausea and vomiting are associated with ADL among majority of cases.
ADL Binding (associated) of associated with appetite loss, pressure and volume under development and vomiting
3) Confidence 0.22 Published 2005 Journal BMC Public Health Section Body Doc Link PMC1156912 Disease Relevance 1.51 Pain Relevance 0.33
The favorable outcomes were defined as basic ADL independence (Barthel Index ?
ADL Binding (independence) of
4) Confidence 0.10 Published 2005 Journal Prev Chronic Dis Section Body Doc Link PMC1364522 Disease Relevance 0.47 Pain Relevance 0.07
As highlighted by Katz and his associates (1963), the index of ADL is a survey instrument, an objective guide to the course of chronic illness and a tool for studying the ageing process.
ADL Binding (index) of associated with aging and chronic disease
5) Confidence 0.09 Published 2010 Journal Eur J Ageing Section Body Doc Link PMC2995861 Disease Relevance 0.19 Pain Relevance 0
85.7, ADL ?
ADL Binding (85.7) of
6) Confidence 0.09 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1253528 Disease Relevance 0.33 Pain Relevance 0.29
Dyspnea with ADL was measured with the CRQ-Dyspnea subscale, which has been validated in previous studies [33,34].
ADL Binding (Dyspnea) of associated with dyspnea
7) Confidence 0.05 Published 2008 Journal Journal of Medical Internet Research Section Body Doc Link PMC2483918 Disease Relevance 1.12 Pain Relevance 0
Due to violations of normality assumptions for the SIB and ADCS-ADL19, post hoc non-parametric analyses were performed; statistically significant benefit of memantine over placebo was demonstrated for the SIB at Week 24, but not for the ADCS-ADL19 (van Dyck et al 2007).
ADCS-ADL19 Binding (assumptions) of
8) Confidence 0.03 Published 2007 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2654628 Disease Relevance 0 Pain Relevance 0
It must be concluded that the statistical benefit of memantine on cognition, global functioning and ADL is not found in all studies in moderate to severe AD.
ADL Binding (cognition) of associated with cognitive disorder and disease
9) Confidence 0.02 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695219 Disease Relevance 0.58 Pain Relevance 0
Only the study in patients with mild to moderate AD showed a positive effect of addition of memantine on cognition, ADL, global functioning and neuropsychiatric functioning.
ADL Binding (cognition) of associated with cognitive disorder and disease
10) Confidence 0.02 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Abstract Doc Link PMC2695219 Disease Relevance 0.83 Pain Relevance 0.07
So, it must be concluded that memantine is a relatively safe drug with few side effects and neglectable risk of drug-drug interactions but only small clinical relevant effects on cognition, global functioning and ADL, mainly in patients with moderate AD.
ADL Binding (interactions) of associated with cognitive disorder and disease
11) Confidence 0.02 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695219 Disease Relevance 0.71 Pain Relevance 0
Initial severe fracture deformation by far was the worst prognostic factor for severe lasting pain and disability, and deterioration of ADL and QoL.
ADL Binding (deterioration) of associated with pain and lasting pain
12) Confidence 0.02 Published 2008 Journal Eur Spine J Section Abstract Doc Link PMC2615123 Disease Relevance 0.33 Pain Relevance 0.33
At 12 months after stroke there was a statistically significant association between symptoms of depression and ADL (p = 0.0045) and between symptoms of depression and SRH (p = 0.0071).
ADL Binding (association) of associated with depression and stroke
13) Confidence 0.01 Published 2007 Journal BMC Fam Pract Section Body Doc Link PMC2174472 Disease Relevance 1.68 Pain Relevance 0.36
Self-rated health was strongly associated with ADL, which corresponds to the findings in other studies, where, for example, the impact of ADL-dependency on quality of life for post-stroke patients was shown in a 2-year follow-up study where quality of life was assessed by a VAS-scale [27], and in a 3-year follow-up study where it was assessed by the SIP-instrument (Sickness Impact Profile) [28].
ADL Binding (associated) of associated with stroke
14) Confidence 0.01 Published 2007 Journal BMC Fam Pract Section Body Doc Link PMC2174472 Disease Relevance 0.70 Pain Relevance 0.14
Variables included in the initial models are selected among the full set of independent measures, using three criteria: 1) a minimum of 5% frequency criterion; 2) risk factors with a correlation of 0.80 or higher presumably measure the same item [13] and when this occurs, one of the variables is randomly eliminated; and 3) bivariate analyses including the weighted baseline ADL status [14] due to its well documented association with functional decline [15-17], with p < 0.10 used as the selection criterion because the association between functional decline and many risk factors is unclear.
ADL Binding (association) of
15) Confidence 0.00 Published 2006 Journal BMC Health Serv Res Section Body Doc Link PMC1774572 Disease Relevance 0 Pain Relevance 0

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