INT183695

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.04
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.75
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Tlr3) signal transduction (Tlr3) endoplasmic reticulum (Tlr3)
RNA binding (Tlr3) intracellular (Tlr3) cytoplasm (Tlr3)
Tlr3 (Mus musculus)
Ducm1 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 56 97.12 Very High Very High Very High
fibrosis 16 95.60 Very High Very High Very High
Inflammation 46 82.56 Quite High
Inflammatory response 2 79.28 Quite High
cytokine 8 69.24 Quite High
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 99.02 Very High Very High Very High
Viral Infection 30 96.52 Very High Very High Very High
Fibrosis 2 95.60 Very High Very High Very High
Respiratory Syncytial Virus 4 93.36 High High
Airway Remodeling 2 91.56 High High
Lung Injury 78 87.44 High High
Pneumonia 22 86.64 High High
Pressure And Volume Under Development 14 85.20 High High
INFLAMMATION 38 78.92 Quite High
Bronchopulmonary Dysplasia 10 77.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DsRNA binds to its cell surface receptor, TLR3, and activates the production of downstream gene products, such as CXC chemokines.
TLR3 Binding (binds) of DsRNA associated with chemokine
1) Confidence 0.04 Published 2005 Journal J Inflamm (Lond) Section Body Doc Link PMC1156932 Disease Relevance 1.76 Pain Relevance 0.42
These findings are also consistent with in vivo studies using monoclonal antibody to TLR3 and genetic knockout mice of TLR3 [52,54] that establish the role of TLR3 in dsRNA recognition and raise the interesting possibility that TLR3 may be involved in the signaling pathway mediating dsRNA induction of CXC chemokines.


TLR3 Binding (recognition) of dsRNA associated with targeted disruption and chemokine
2) Confidence 0.02 Published 2005 Journal J Inflamm (Lond) Section Body Doc Link PMC1156932 Disease Relevance 0.99 Pain Relevance 0.14

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox