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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.99
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Tlr3, Tlr3) signal transduction (Tlr3, Tlr3) endoplasmic reticulum (Tlr3, Tlr3)
RNA binding (Tlr3, Tlr3) intracellular (Tlr3, Tlr3) cytoplasm (Tlr3, Tlr3)
Tlr3 (Mus musculus)
Tlr3 (Mus musculus)
Ducm1 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 28 95.08 Very High Very High Very High
cytokine 4 69.56 Quite High
fibrosis 8 59.92 Quite High
Inflammation 23 13.16 Low Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 1 99.18 Very High Very High Very High
Respiratory Syncytial Virus 2 93.68 High High
Viral Infection 15 75.00 Quite High
Lung Injury 39 74.80 Quite High
Infection 3 64.68 Quite High
Pulmonary Disease 9 63.36 Quite High
Asthma 6 61.60 Quite High
Cystic Fibrosis 3 60.48 Quite High
Pulmonary Fibrosis 4 59.12 Quite High
Bronchopulmonary Dysplasia 5 57.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings are also consistent with in vivo studies using monoclonal antibody to TLR3 and genetic knockout mice of TLR3 [52,54] that establish the role of TLR3 in dsRNA recognition and raise the interesting possibility that TLR3 may be involved in the signaling pathway mediating dsRNA induction of CXC chemokines.

TLR3 Regulation (role) of TLR3 Binding (recognition) of dsRNA associated with targeted disruption and chemokine
1) Confidence 0.02 Published 2005 Journal J Inflamm (Lond) Section Body Doc Link PMC1156932 Disease Relevance 0.99 Pain Relevance 0.14

General Comments

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