INT183761

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Context Info
Confidence 0.80
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 4.04
Pain Relevance 1.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Csf2) extracellular region (Csf2)
Anatomy Link Frequency
hematopoietic stem cell 2
dorsal root ganglion 1
Csf2 (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 18 98.96 Very High Very High Very High
metalloproteinase 54 98.52 Very High Very High Very High
withdrawal 29 97.44 Very High Very High Very High
methotrexate 32 97.24 Very High Very High Very High
rheumatoid arthritis 154 96.60 Very High Very High Very High
Osteoarthritis 34 90.40 High High
dexamethasone 45 86.40 High High
Inflammation 21 75.52 Quite High
Dorsal horn neuron 3 52.48 Quite High
Sciatic nerve 11 50.00 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 25 98.96 Very High Very High Very High
Disease 182 97.84 Very High Very High Very High
Rheumatoid Arthritis 154 96.60 Very High Very High Very High
Osteoarthritis 34 90.40 High High
Congenital Anomalies 8 87.48 High High
Cancer 10 77.20 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 78 77.08 Quite High
Necrosis 7 76.72 Quite High
Mycobacterial Infection 45 76.32 Quite High
INFLAMMATION 29 75.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was the only trial with a smaller dose of GM-CSF (125 ?
Phosphorylation (dose) of GM-CSF
1) Confidence 0.80 Published 2005 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC1164429 Disease Relevance 0.26 Pain Relevance 0
Therefore, increased levels of tau and hyperphosphorylated tau in CSF can correlate with the onset of neurodegeneration in AD.
Phosphorylation (hyperphosphorylated) of CSF associated with disease
2) Confidence 0.50 Published 2010 Journal International Journal of Alzheimer's Disease Section Body Doc Link PMC2915796 Disease Relevance 0.97 Pain Relevance 0
There was a significant correlation between MMP-9 concentration and CSF WCC (R2?
Phosphorylation (correlation) of CSF WCC
3) Confidence 0.33 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2748711 Disease Relevance 0.15 Pain Relevance 0.21
2-microglobulin; ELISA = enzyme-kinked immunosorbent assay; GM-CSF = granulocyte-macrophage colony stimulating factor; HSCT = hematopoietic stem cell transplantation; MFI = mean fluorescence intensity; MMP = matrix metalloproteinase; MTX = methotrexate; NF?
Phosphorylation (transplantation) of granulocyte-macrophage colony stimulating factor in hematopoietic stem cell associated with metalloproteinase and methotrexate
4) Confidence 0.14 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526601 Disease Relevance 1.20 Pain Relevance 0.56
2-microglobulin; ELISA = enzyme-kinked immunosorbent assay; GM-CSF = granulocyte-macrophage colony stimulating factor; HSCT = hematopoietic stem cell transplantation; MFI = mean fluorescence intensity; MMP = matrix metalloproteinase; MTX = methotrexate; NF?
Phosphorylation (transplantation) of GM-CSF in hematopoietic stem cell associated with metalloproteinase and methotrexate
5) Confidence 0.14 Published 2006 Journal Arthritis Res Ther Section Body Doc Link PMC1526601 Disease Relevance 1.20 Pain Relevance 0.56
EPW: electrical stimulation-induced paw withdrawal; EPF: electrical stimulation-induced paw flexion; DRG: dorsal root ganglion; ERK: extracellular signal-regulated kinase; pERK: phosphorylated extracellular signal-regulated kinase; aCSF: artificial cerebrospinal fluid.


Phosphorylation (phosphorylated) of aCSF in dorsal root ganglion associated with ganglion cysts, dorsal root ganglion and withdrawal
6) Confidence 0.02 Published 2008 Journal Mol Pain Section Body Doc Link PMC2488330 Disease Relevance 0.26 Pain Relevance 0.25

General Comments

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