INT183769

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Context Info
Confidence 0.48
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Csf2) extracellular region (Csf2) cytoplasmic membrane-bounded vesicle (CXCR4)
plasma membrane (CXCR4) cytoplasm (CXCR4) signal transducer activity (CXCR4)
Anatomy Link Frequency
macrophages 2
Csf2 (Mus musculus)
CXCR4 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 62.80 Quite High
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 73 96.40 Very High Very High Very High
Infection 22 94.56 High High
Sprains And Strains 2 94.08 High High
Leukopenia 2 34.56 Quite Low
Neutropenia 1 11.20 Low Low
Opportunistic Infections 17 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Hepatitis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro, the presence of GM-CSF suppresses the expression of CXCR4 mRNA and CCR5 mRNA by monocytes differentiating in macrophages, resulting in macrophages that are relatively resistant to M-tropic HIV infection [25].
GM-CSF Negative_regulation (suppresses) of Transcription (expression) of CXCR4 in macrophages associated with acquired immune deficiency syndrome or hiv infection and infection
1) Confidence 0.48 Published 2005 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC1164429 Disease Relevance 0.92 Pain Relevance 0.03

General Comments

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