INT183785

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.83
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (INS) carbohydrate metabolic process (INS) cytoplasm (NFKBIB)
signal transducer activity (NFKBIB) cell-cell signaling (INS) cytosol (NFKBIB)
Anatomy Link Frequency
mononuclear cells 2
INS (Homo sapiens)
NFKBIB (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 105 99.56 Very High Very High Very High
tolerance 2 79.04 Quite High
cytokine 42 74.96 Quite High
antagonist 2 49.40 Quite Low
Inflammatory response 19 5.00 Very Low Very Low Very Low
Inflammatory mediators 8 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Inflammatory marker 3 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 138 99.56 Very High Very High Very High
Diabetes Mellitus 16 94.68 High High
Obesity 17 93.88 High High
Aging 29 90.96 High High
Stress 5 90.96 High High
Overnutrition 3 88.12 High High
Impaired Glucose Tolerance 2 79.04 Quite High
Insulin Resistance 9 74.80 Quite High
Cancer 32 61.04 Quite High
Disease 63 60.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In fact, insulin reduces ROS generation by mononuclear cells, suppresses NADPH oxidase expression and intranuclear NF-kB binding, induces IkB expression and suppresses some inflammatory molecules [69,76].
insulin Positive_regulation (induces) of Gene_expression (expression) of IkB in mononuclear cells associated with inflammation
1) Confidence 0.03 Published 2005 Journal Immun Ageing Section Body Doc Link PMC1166571 Disease Relevance 1.83 Pain Relevance 0.34

General Comments

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