INT183786

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Context Info
Confidence 0.09
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.61
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6, INS) extracellular region (IL6, INS) small molecule metabolic process (INS)
aging (IL6) carbohydrate metabolic process (INS) cell-cell signaling (INS)
Anatomy Link Frequency
hepatocytes 1
IL6 (Homo sapiens)
INS (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 42 95.76 Very High Very High Very High
antagonist 2 86.20 High High
tolerance 2 72.08 Quite High
Inflammation 105 71.68 Quite High
Inflammatory response 19 5.00 Very Low Very Low Very Low
Inflammatory mediators 8 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Inflammatory marker 3 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 17 97.60 Very High Very High Very High
Insulin Resistance 9 84.04 Quite High
Diabetes Mellitus 16 77.56 Quite High
Impaired Glucose Tolerance 2 73.44 Quite High
INFLAMMATION 138 71.68 Quite High
Disease 63 61.48 Quite High
Stress 5 57.52 Quite High
Overnutrition 3 54.24 Quite High
Cancer 32 51.16 Quite High
Aging 29 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
More recently, IL-6 has been shown to inhibit insulin signal transduction in hepatocytes [53].
IL-6 Negative_regulation (inhibit) of insulin in hepatocytes
1) Confidence 0.09 Published 2005 Journal Immun Ageing Section Body Doc Link PMC1166571 Disease Relevance 1.61 Pain Relevance 0.35

General Comments

This test has worked.

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