INT183791

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Context Info
Confidence 0.49
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 4.72
Pain Relevance 1.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNF) extracellular space (TNF) extracellular region (TNF)
plasma membrane (TNF) intracellular (TNF) extracellular matrix organization (TNF)
Anatomy Link Frequency
joints 2
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 141 98.76 Very High Very High Very High
Inflammation 259 98.64 Very High Very High Very High
rheumatoid arthritis 116 96.68 Very High Very High Very High
tolerance 2 87.84 High High
depression 141 82.72 Quite High
antagonist 9 58.20 Quite High
imagery 10 27.28 Quite Low
Arthritis 37 10.24 Low Low
Pain 45 5.00 Very Low Very Low Very Low
Inflammatory response 35 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 56 100.00 Very High Very High Very High
Necrosis 19 100.00 Very High Very High Very High
Stress 63 99.98 Very High Very High Very High
Targeted Disruption 48 99.96 Very High Very High Very High
INFLAMMATION 297 98.64 Very High Very High Very High
Obesity 18 97.68 Very High Very High Very High
Overnutrition 3 96.92 Very High Very High Very High
Diabetes Mellitus 24 96.72 Very High Very High Very High
Rheumatoid Arthritis 116 96.68 Very High Very High Very High
Disease 115 89.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The increased concentrations of TNF-?
Positive_regulation (increased) of Phosphorylation (concentrations) of TNF
1) Confidence 0.49 Published 2005 Journal Immun Ageing Section Body Doc Link PMC1166571 Disease Relevance 1.48 Pain Relevance 0.38
The students with lower serum levels of omega-3s had a significantly greater stress-induced elevation of TNF-?
Positive_regulation (induced) of Phosphorylation (elevation) of TNF associated with stress
2) Confidence 0.49 Published 2007 Journal Int Breastfeed J Section Body Doc Link PMC1855049 Disease Relevance 1.43 Pain Relevance 0.50
Increased lymphangiogenesis in joints of tumor necrosis factor-transgenic mice
Positive_regulation (Increased) of Phosphorylation (joints) of tumor necrosis factor in joints associated with targeted disruption, necrosis and cancer
3) Confidence 0.42 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246237 Disease Relevance 0.84 Pain Relevance 0.05
As anticipated, the frequency of TNF?
Positive_regulation (anticipated) of Phosphorylation (frequency) of TNF
4) Confidence 0.07 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2991017 Disease Relevance 0.69 Pain Relevance 0.30
Upon stimulation with LPS or TNF, a splice-variant of MyD88, MyD88s, can be induced which prevents activation of NF?
Positive_regulation (induced) of Phosphorylation (stimulation) of TNF
5) Confidence 0.04 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2945668 Disease Relevance 0.14 Pain Relevance 0.17
Upon stimulation with LPS or TNF, a splice-variant of MyD88, MyD88s, can be induced which prevents activation of NF?
Positive_regulation (Upon) of Phosphorylation (stimulation) of TNF
6) Confidence 0.04 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2945668 Disease Relevance 0.14 Pain Relevance 0.17

General Comments

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