INT183795

Context Info Confidence 0.30 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.24 Pain Relevance 0.10

extracellular space (IL17A, MMP9) extracellular region (IL17A, MMP9) peptidase activity (MMP9) cell death (IL17A) proteinaceous extracellular matrix (MMP9) extracellular matrix organization (MMP9)

Anatomy Link Frequency neutrophil 2 IL17A (Homo sapiens) MMP9 (Homo sapiens)

Pain Link Frequency Relevance Heat metalloproteinase 22 100.00 Inflammation 7 44.72 cytokine 3 5.00 Inflammatory stimuli 2 5.00 lidocaine 1 5.00 Morphine 1 5.00

Disease Link Frequency Relevance Heat Urological Neuroanatomy 3 83.92 INFLAMMATION 9 44.72 Pulmonary Disease 6 34.24 Asthma 3 5.00 Nicotine Addiction 2 5.00 Disease 1 5.00 Bronchitis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

This IL-17A induces an increase of MMP-9 protein and in corresponding gelatinase activity, that is due to an increased number of neutrophils rather than an increased amount of MMP-9 per neutrophil [12].

IL-17A Positive_regulation (induces) of Positive_regulation (increase) of MMP-9 protein in neutrophil associated with metalloproteinase

1) Confidence 0.30 Published 2005 Journal Respir Res Section Body Doc Link PMC1166577 Disease Relevance 0.24 Pain Relevance 0.10

General Comments

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