INT183814

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Context Info
Confidence 0.69
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 1.04
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (HPRT1) small molecule metabolic process (HPRT1) transferase activity, transferring glycosyl groups (HPRT1)
cytoplasm (HPRT1)
Anatomy Link Frequency
muscle 1
HPRT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 51 97.52 Very High Very High Very High
cytokine 17 93.68 High High
metalloproteinase 22 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Inflammatory stimuli 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 2 99.04 Very High Very High Very High
Cancer 2 98.68 Very High Very High Very High
INFLAMMATION 53 97.52 Very High Very High Very High
Lung Injury 16 90.24 High High
Hyperinsulinism 2 88.76 High High
Familial Dysautonomia 75 50.00 Quite Low
Atelectasis 2 25.24 Quite Low
Pneumonia 11 5.00 Very Low Very Low Very Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low
Cognitive Disorder 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
mRNA and hypoxanthine phosphoribosyltransferase (HPRT) mRNA expression was quantified using QRTPCR.
Transcription (expression) of HPRT
1) Confidence 0.69 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC2873469 Disease Relevance 0.48 Pain Relevance 0.14
mRNA and hypoxanthine phosphoribosyltransferase (HPRT) mRNA expression was quantified using QRTPCR.
Transcription (expression) of hypoxanthine phosphoribosyltransferase
2) Confidence 0.52 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC2873469 Disease Relevance 0.48 Pain Relevance 0.14
HPRT1 mRNA served as the reference transcript.
Transcription (served) of HPRT1
3) Confidence 0.45 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2148100 Disease Relevance 0 Pain Relevance 0
For normalization HPRT mRNA was amplified using HPRT-F (5?
Transcription (amplified) of HPRT
4) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3012102 Disease Relevance 0 Pain Relevance 0
The HPRT1 transcript was selected as the reference gene on an empirical basis—HPRT1 expression in these men (1863±111 arbitrary units, mean±SEM) and women (1881±138 arbitrary units) was similar according to the microarray data (this choice does not necessarily mean that HPRT1 expression always is constant in muscle).
Transcription (selected) of HPRT1 in muscle
5) Confidence 0.35 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2148100 Disease Relevance 0.09 Pain Relevance 0
The expression of transcripts for IL-17 mRNA was normalized to the expression of HPRT transcripts and shown as percent of the house-keeping gene (% HPRT).
Transcription (expression) of HPRT
6) Confidence 0.10 Published 2005 Journal Respir Res Section Body Doc Link PMC1166577 Disease Relevance 0 Pain Relevance 0

General Comments

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