INT183820

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Context Info
Confidence 0.39
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 3.27
Pain Relevance 1.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (BCAR1) cytosol (BCAR1) signal transduction (BCAR1)
cell adhesion (BCAR1) plasma membrane (BCAR1) cell division (BCAR1)
Anatomy Link Frequency
monocytes 2
BCAR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 34 100.00 Very High Very High Very High
alcohol 16 78.64 Quite High
corticosteroid 2 63.92 Quite High
Inflammation 26 58.40 Quite High
Inflammatory response 12 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
cytokine 8 5.00 Very Low Very Low Very Low
Enkephalin 6 5.00 Very Low Very Low Very Low
substance P 6 5.00 Very Low Very Low Very Low
cva 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Anomalies 84 100.00 Very High Very High Very High
Chromosome Aberrations 12 100.00 Very High Very High Very High
Syndrome 16 87.28 High High
Patent Ductus Arteriosus 2 84.68 Quite High
Cryptorchidism 4 83.52 Quite High
Pregnancy Complications 6 83.08 Quite High
Hypersensitivity 2 81.80 Quite High
Hypospadias 2 79.40 Quite High
Cleft Palate 14 78.76 Quite High
Togavirus Infection 6 77.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus the mothers of babies affected with CAs are continually thinking of possible dangerous environmental factors and when asked about the history of their pregnancy, give a long list of supposed agents.
Regulation (affected) of CAs associated with congenital anomalies
1) Confidence 0.39 Published 2005 Journal International Journal of Medical Sciences Section Body Doc Link PMC1168874 Disease Relevance 0.54 Pain Relevance 0.03
Therefore we have to focus our analysis on specific CAs since teratogenic drugs induce specific CAs without affecting other CAs and overall rates.
Neg (without) Regulation (affecting) of CAs associated with congenital anomalies
2) Confidence 0.24 Published 2005 Journal International Journal of Medical Sciences Section Body Doc Link PMC1168874 Disease Relevance 1.80 Pain Relevance 0.04
HLA-DR MFI absolute values for AAS and CAS before anesthesia and healthy controls on CD14HIGH monocytes were 282 ± 31, 285 ± 23 and 211 ± 37, respectively.
Regulation (controls) of CAS in monocytes associated with anesthesia
3) Confidence 0.04 Published 2010 Journal Crit Care Section Body Doc Link PMC2887183 Disease Relevance 0.33 Pain Relevance 0.47
HLA-DR MFI absolute values for AAS and CAS before anesthesia and healthy controls on CD14LOW monocytes were 426 ± 34, 418 ± 31 and 452 ± 31, respectively.
Regulation (controls) of CAS in monocytes associated with anesthesia
4) Confidence 0.04 Published 2010 Journal Crit Care Section Body Doc Link PMC2887183 Disease Relevance 0.25 Pain Relevance 0.52
Our findings suggest: a) SCE and CAs are sensitive biomarkers for human chromosome damage induced by As exposure; b) DNA single-strand breaks and DPCs can be used to monitor DNA damage in populations exposed to As; c) p53 mutations and p16 deletions were associated with carcinogenicity due to As exposure; and d) the decrease in DNA repair may be another important mechanism in arsenicosis carcinogenicity.
Regulation (sensitive) of CAs associated with chromosome aberrations
5) Confidence 0.03 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC1852665 Disease Relevance 0.35 Pain Relevance 0

General Comments

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