INT183861

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Context Info
Confidence 0.03
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.21
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CAV1, CDC42EP5) plasma membrane (CAV1, CDC42EP5) endosome (CAV1)
mitochondrion (CAV1) small molecule metabolic process (CAV1) Golgi apparatus (CAV1)
CAV1 (Homo sapiens)
CDC42EP5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 6 11.68 Low Low
Chronic pancreatitis 6 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 69 99.82 Very High Very High Very High
Pancreatic Cancer 21 98.00 Very High Very High Very High
Adenocarcinoma 153 96.44 Very High Very High Very High
Cancer 93 95.16 Very High Very High Very High
Disease 3 90.32 High High
Carcinoma 3 88.16 High High
Inflammatory Breast Neoplasms 6 11.68 Low Low
Pancreatitis 6 5.00 Very Low Very Low Very Low
Renal Cancer 3 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The small monomeric GTPases are among several molecules which associate with cav-1.
cav-1 Binding (associate) of GTPases
1) Confidence 0.03 Published 2005 Journal Mol Cancer Section Abstract Doc Link PMC1173138 Disease Relevance 1.00 Pain Relevance 0
Due to their role in cellular migration, invasion and metastasis the Rho GTPases were logical molecular candidates to interact with cav-1 to mediate cell migration and invasion.
cav-1 Binding (interact) of GTPases associated with metastasis
2) Confidence 0.02 Published 2005 Journal Mol Cancer Section Body Doc Link PMC1173138 Disease Relevance 0.46 Pain Relevance 0
Many proteins including the majority of the Rho GTPases have the ability to associate with cav-1 [3,4,14-18].
cav-1 Binding (associate) of GTPases
3) Confidence 0.02 Published 2005 Journal Mol Cancer Section Body Doc Link PMC1173138 Disease Relevance 1.75 Pain Relevance 0

General Comments

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