INT183864

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Context Info
Confidence 0.39
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.95
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (CAV1, RHOC) cytoplasm (CAV1, RHOC) cytosol (CAV1, RHOC)
plasma membrane (CAV1, RHOC) endosome (CAV1) mitochondrion (CAV1)
CAV1 (Homo sapiens)
RHOC (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adenocarcinoma 51 97.52 Very High Very High Very High
Metastasis 23 88.36 High High
Cancer 31 86.76 High High
Pancreatic Cancer 7 75.00 Quite High
Pancreatitis 2 5.00 Very Low Very Low Very Low
Inflammatory Breast Neoplasms 2 5.00 Very Low Very Low Very Low
Renal Cancer 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Breast Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cav-1 expression inhibits RhoC GTPase activation and subsequent activation of the p38 MAPK pathway in primary PC cells thus restricting migration and invasion.
Gene_expression (expression) of Cav-1 Negative_regulation (inhibits) of Positive_regulation (activation) of RhoC associated with adenocarcinoma
1) Confidence 0.39 Published 2005 Journal Mol Cancer Section Abstract Doc Link PMC1173138 Disease Relevance 0.95 Pain Relevance 0

General Comments

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