INT184009

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Context Info
Confidence 0.35
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.22
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cish)
Cish (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 10 92.88 High High
cytokine 50 90.48 High High
Hippocampus 9 76.68 Quite High
Inflammation 34 47.12 Quite Low
Catechol-O-methyltransferase 27 5.00 Very Low Very Low Very Low
Dopamine 15 5.00 Very Low Very Low Very Low
Nucleus accumbens 5 5.00 Very Low Very Low Very Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
Catecholamine 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 57 99.88 Very High Very High Very High
Cancer 13 94.92 High High
Rheumatoid Arthritis 10 92.88 High High
Obesity 3 83.36 Quite High
Diabetes Mellitus 2 82.88 Quite High
Reprotox - General 1 1 82.12 Quite High
Hyperlipidemia 1 76.40 Quite High
Lung Cancer 1 58.56 Quite High
T-cell Lymphoma 1 50.92 Quite High
Blast Crisis 1 50.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The reduction of SOCS expression is also a therapeutic target. siRNA technology made the reduction of SOCS1 expression in DCs possible, and also improved anti-tumor immunity [69].
Negative_regulation (reduction) of Gene_expression (expression) of SOCS associated with cancer
1) Confidence 0.35 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174965 Disease Relevance 0.73 Pain Relevance 0.16
All crosses derived from strains that differed in Comt expression show strong cis-modulation.
Negative_regulation (differed) of Gene_expression (expression) of cis-modulation associated with sprains and strains
2) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923157 Disease Relevance 0.49 Pain Relevance 0.04

General Comments

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