INT184052

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Context Info
Confidence 0.59
First Reported 2005
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 4.07
Pain Relevance 1.54

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Socs1)
Socs1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 102 100.00 Very High Very High Very High
Osteoarthritis 22 99.98 Very High Very High Very High
cytokine 65 97.72 Very High Very High Very High
rheumatoid arthritis 67 93.68 High High
Arthritis 8 87.68 High High
Inflammatory response 5 62.80 Quite High
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 101 100.00 Very High Very High Very High
Disease 62 100.00 Very High Very High Very High
Frailty 22 99.98 Very High Very High Very High
Anaerobic Bacterial Infections 5 94.88 High High
Rheumatoid Arthritis 67 93.68 High High
Wound Healing 1 93.08 High High
Arthritis 13 87.68 High High
Pox Virus Infection 1 85.76 High High
Hepatitis 6 78.88 Quite High
Sprains And Strains 2 77.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SOCS1 and inflammatory diseases
Localization (diseases) of SOCS1 associated with inflammation and disease
1) Confidence 0.59 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174965 Disease Relevance 1.14 Pain Relevance 0.55
These include the release of soluble decoy TLR receptors, intracellular inhibitory molecules such as IRAK-M, SOCS1, Tam family kinases, and transmembrane regulators such as SIGIRR (reviewed in [8, 193]).
Localization (release) of SOCS1
2) Confidence 0.28 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2913853 Disease Relevance 1.03 Pain Relevance 0.19
None of the 6 OA patients was positive for either autoantibody in serum or synovial extracts, so an OA SSI could not be calculated.
Neg (not) Localization (calculated) of SSI associated with osteoarthritis
3) Confidence 0.04 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592782 Disease Relevance 1.91 Pain Relevance 0.80

General Comments

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