INT184055

Context Info Confidence 0.33 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.12 Pain Relevance 0.17

signal transduction (Stat5a) nucleus (Stat5a) DNA binding (Stat5a) cytoplasm (Stat5a) signal transducer activity (Stat5a)

Stat5a (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 50 99.88 Inflammation 34 5.00 rheumatoid arthritis 10 5.00 Arthritis 4 5.00 fibrosis 2 5.00 cerebral cortex 1 5.00 cINOD 1 5.00 tolerance 1 5.00 Crohn's disease 1 5.00

Disease Link Frequency Relevance Heat Pathologic Processes 1 59.92 Targeted Disruption 11 55.20 INFLAMMATION 31 5.00 Disease 20 5.00 Cancer 13 5.00 Rheumatoid Arthritis 10 5.00 Hepatocellular Cancer 9 5.00 Arthritis 6 5.00 Hepatitis 5 5.00 Obesity 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

CIS is induced by cytokines that activate STAT5 and bind to receptors that activate STAT5, namely erythropoietin, IL-2, IL-3, prolactin and growth hormone (GH) [11].

Positive_regulation (activate) of STAT5 Binding (bind) of associated with cytokine

1) Confidence 0.33 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174965 Disease Relevance 0.12 Pain Relevance 0.17

General Comments

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