INT184076

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Context Info
Confidence 0.33
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.80
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Socs2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 68 98.20 Very High Very High Very High
cytokine 100 97.32 Very High Very High Very High
rheumatoid arthritis 20 5.00 Very Low Very Low Very Low
Arthritis 8 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 40 98.56 Very High Very High Very High
INFLAMMATION 62 98.20 Very High Very High Very High
Body Weight 4 87.92 High High
Hypertrophy 2 83.36 Quite High
Pathologic Processes 2 73.40 Quite High
Hepatotoxicity 2 73.12 Quite High
Lymphopenia 2 69.92 Quite High
Targeted Disruption 22 68.68 Quite High
Syndrome 2 68.48 Quite High
Embryonic Lethality 2 23.20 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CIS and SOCS2 bind to phosphorylated tyrosine residues on activated (phosphorylated) cytokine receptors.
SOCS2 Binding (bind) of associated with cytokine
1) Confidence 0.33 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174965 Disease Relevance 0.14 Pain Relevance 0.24
SOCS2 is known to bind to GH receptors and to inhibit the activation of STAT5b induced by GH.
SOCS2 Binding (bind) of
2) Confidence 0.24 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174965 Disease Relevance 0.66 Pain Relevance 0.05

General Comments

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