INT18408

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Context Info
Confidence 0.45
First Reported 1984
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.51
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SST) extracellular region (SST) cell-cell signaling (SST)
Anatomy Link Frequency
basal ganglia 2
neural 2
SST (Homo sapiens)
Pain Link Frequency Relevance Heat
Somatostatin 3 100.00 Very High Very High Very High
Cholecystokinin 1 99.22 Very High Very High Very High
Enkephalin 1 98.82 Very High Very High Very High
substance P 1 98.50 Very High Very High Very High
Hippocampus 1 91.52 High High
Catecholamine 1 91.12 High High
agonist 5 90.00 High High
antagonist 5 88.96 High High
Neuropeptide 3 84.72 Quite High
Clonidine 4 77.60 Quite High
Disease Link Frequency Relevance Heat
Disease 3 97.52 Very High Very High Very High
Dementia 1 94.04 High High
Congenital Anomalies 1 86.64 High High
Neurological Disease 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The adrenergic system is involved in the neural control of GH secretion with both stimulatory and inhibitory influences mainly mediated via GHRH and/or somatostatin modulation.
Positive_regulation (mediated) of Regulation (modulation) of somatostatin in neural associated with somatostatin
1) Confidence 0.45 Published 1990 Journal Endocrinol. Exp. Section Abstract Doc Link 1972919 Disease Relevance 0 Pain Relevance 0.57
In Huntington's disease, there are reduced concentrations of substance P, met-enkephalin and cholecystokinin in the basal ganglia; in contrast the concentrations of somatostatin and TRH are increased.
Positive_regulation (increased) of Regulation (concentrations) of somatostatin in basal ganglia associated with somatostatin, enkephalin, disease, cholecystokinin and substance p
2) Confidence 0.39 Published 1984 Journal Peptides Section Abstract Doc Link 6207511 Disease Relevance 0.51 Pain Relevance 0.48

General Comments

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