INT184081

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Context Info
Confidence 0.11
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Irs4) plasma membrane (Irs4) cellular_component (Socs6)
signal transducer activity (Irs4)
Anatomy Link Frequency
SH2 1
Irs4 (Mus musculus)
Socs6 (Mus musculus)
Pain Link Frequency Relevance Heat
cerebral cortex 1 59.52 Quite High
cytokine 50 50.00 Quite Low
Inflammation 34 5.00 Very Low Very Low Very Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 11 78.44 Quite High
Hydrocephalus 1 69.20 Quite High
Disease 20 38.80 Quite Low
Diabetes Mellitus 2 31.00 Quite Low
Obesity 3 30.48 Quite Low
Metabolic Disorder 1 29.84 Quite Low
Insulin Resistance 3 23.96 Low Low
Necrosis 2 16.60 Low Low
Cancer 13 16.24 Low Low
INFLAMMATION 31 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SOCS6 and SOCS7 SH2 domains interacted with a protein complex consisting of IRS-4, IRS-2 and the p85 regulatory subunit of phosphoinositide 3-kinase.
IRS-4 Binding (interacted) of SOCS6 in SH2
1) Confidence 0.11 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174965 Disease Relevance 0.20 Pain Relevance 0.03

General Comments

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