INT184095

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Context Info
Confidence 0.21
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Socs3) extracellular space (Il10) extracellular region (Il10)
intracellular (Il10) cytoplasm (Socs3)
Il10 (Mus musculus)
Socs3 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 50 92.68 High High
Inflammation 34 80.32 Quite High
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 31 80.32 Quite High
Disease 20 77.08 Quite High
Shock 3 63.68 Quite High
Cancer 13 48.44 Quite Low
Targeted Disruption 11 19.84 Low Low
Autoimmune Disease 1 18.36 Low Low
Rheumatoid Arthritis 10 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 9 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
Hepatitis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SOCS3 protein was strongly induced by both IL-6 and IL-10 in the presence of LPS, but selectively inhibited IL-6 signaling, because SOCS3 bound the IL-6 receptor, gp130 (Y759), but not the IL-10 receptor [43].
IL-10 Positive_regulation (induced) of SOCS3
1) Confidence 0.21 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174965 Disease Relevance 0.49 Pain Relevance 0.34

General Comments

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