INT184104

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Context Info
Confidence 0.10
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Socs3, Gopc) transport (Gopc) signal transduction (Socs3)
Golgi apparatus (Gopc) plasma membrane (Gopc)
Anatomy Link Frequency
SH2 1
Socs3 (Mus musculus)
Gopc (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 50 100.00 Very High Very High Very High
Inflammation 34 5.00 Very Low Very Low Very Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pathologic Processes 1 23.36 Low Low
Targeted Disruption 11 18.64 Low Low
INFLAMMATION 31 5.00 Very Low Very Low Very Low
Disease 20 5.00 Very Low Very Low Very Low
Cancer 13 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 10 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 9 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
Hepatitis 5 5.00 Very Low Very Low Very Low
Obesity 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whereas SOCS1 binds directly to the activation loop of JAKs through its SH2 domain, the SOCS3 SH2 domain binds the cytokine receptor (Fig. 3).
SOCS3 Binding (binds) of Fig in SH2 associated with cytokine
1) Confidence 0.10 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174965 Disease Relevance 0 Pain Relevance 0.14

General Comments

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