INT184108

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Context Info
Confidence 0.09
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Mapk1) mitochondrion (Mapk1) enzyme binding (Csf3)
protein complex (Mapk1) cytoplasm (Mapk1) cytosol (Mapk1)
Anatomy Link Frequency
neutrophils 1
Csf3 (Mus musculus)
Mapk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 34 88.36 High High
cytokine 50 50.00 Quite Low
rheumatoid arthritis 10 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Paresis 1 91.44 High High
INFLAMMATION 31 88.36 High High
Splenomegaly 1 86.52 High High
Body Weight 2 76.48 Quite High
Coronary Heart Disease 1 60.20 Quite High
Weight Gain 1 57.36 Quite High
Tetraploidy 1 51.92 Quite High
Embryonic Lethality 1 50.56 Quite High
Insulin Resistance 3 42.72 Quite Low
Obesity 3 38.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is probable that the ERK (extracellular signal-related kinase) pathway induced by G-CSF has a major function in the proliferation and differentiation of neutrophils.
G-CSF Positive_regulation (induced) of ERK in neutrophils
1) Confidence 0.09 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174965 Disease Relevance 0.64 Pain Relevance 0.08

General Comments

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