INT184110

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Context Info
Confidence 0.32
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Jak1, Stat1) cytoplasm (Jak1, Stat1) nucleolus (Stat1)
enzyme binding (Stat1) DNA binding (Stat1) kinase activity (Jak1)
Jak1 (Mus musculus)
Stat1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 34 90.24 High High
cytokine 50 89.20 High High
rheumatoid arthritis 10 71.04 Quite High
Arthritis 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 31 90.24 High High
Rheumatoid Arthritis 10 71.04 Quite High
Disease 20 69.80 Quite High
Cancer 13 5.00 Very Low Very Low Very Low
Targeted Disruption 11 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 9 5.00 Very Low Very Low Very Low
Arthritis 6 5.00 Very Low Very Low Very Low
Hepatitis 5 5.00 Very Low Very Low Very Low
Obesity 3 5.00 Very Low Very Low Very Low
Shock 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
uses JAK1 and JAK2, which activate mainly STAT1, whereas IL-6 binding to the IL-6 receptor ?
JAK1 Positive_regulation (activate) of STAT1
1) Confidence 0.32 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174965 Disease Relevance 0.30 Pain Relevance 0.33

General Comments

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