INT184140

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Context Info
Confidence 0.10
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.33
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gh, Stat5b) signal transduction (Gh, Stat5b) nucleus (Gh, Stat5b)
mitochondrion (Gh) DNA binding (Stat5b) cytoplasm (Stat5b)
Socs2 (Mus musculus)
Gh (Mus musculus)
Stat5b (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 68 98.20 Very High Very High Very High
cytokine 100 50.00 Quite Low
rheumatoid arthritis 20 5.00 Very Low Very Low Very Low
Arthritis 8 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 40 98.56 Very High Very High Very High
INFLAMMATION 62 98.20 Very High Very High Very High
Body Weight 4 93.52 High High
Hypertrophy 2 88.96 High High
Hepatotoxicity 2 73.12 Quite High
Lymphopenia 2 69.92 Quite High
Syndrome 2 68.48 Quite High
Targeted Disruption 22 39.40 Quite Low
Embryonic Lethality 2 28.80 Quite Low
Tetraploidy 2 25.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SOCS2 is known to bind to GH receptors and to inhibit the activation of STAT5b induced by GH.
SOCS2 Negative_regulation (inhibit) of GH Positive_regulation (activation) of STAT5b
1) Confidence 0.10 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174965 Disease Relevance 0.67 Pain Relevance 0.05
SOCS2 is known to bind to GH receptors and to inhibit the activation of STAT5b induced by GH.
SOCS2 Negative_regulation (inhibit) of GH Positive_regulation (induced) of STAT5b
2) Confidence 0.10 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174965 Disease Relevance 0.67 Pain Relevance 0.05

General Comments

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