INT184161

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Context Info
Confidence 0.07
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (Egr1, Ptges2) cytoplasm (Egr1, Ptges2) nucleus (Egr1, Ptges2)
isomerase activity (Ptges2) mitochondrion (Ptges2) Golgi apparatus (Ptges2)
Egr1 (Mus musculus)
Ptges2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 22 79.44 Quite High
cytokine 4 74.72 Quite High
Pain 2 55.36 Quite High
Arthritis 12 37.08 Quite Low
dexamethasone 1 28.40 Quite Low
Osteoarthritis 1 26.68 Quite Low
rheumatoid arthritis 5 25.32 Quite Low
cINOD 5 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 3 94.00 High High
INFLAMMATION 18 79.44 Quite High
Pain 2 55.36 Quite High
Fever 4 54.56 Quite High
Arthritis 12 37.08 Quite Low
Rheumatoid Arthritis 6 25.32 Quite Low
Osteoporosis 1 17.56 Low Low
Hypercalcemia 1 16.76 Low Low
Disease 4 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ligands have been shown to suppress Egr-1-mediated induction of the activities of the mPGES-1 promoter, and a synthetic promoter-reporter construct in IL-1?
Negative_regulation (suppress) of Egr-1-mediated Positive_regulation (induction) of mPGES-1
1) Confidence 0.07 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174970 Disease Relevance 0.34 Pain Relevance 0.19

General Comments

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