INT184162

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Context Info
Confidence 0.08
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.42
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (Egr1, Ptges2) cytoplasm (Egr1, Ptges2) nucleus (Egr1, Ptges2)
isomerase activity (Ptges2) mitochondrion (Ptges2) Golgi apparatus (Ptges2)
Anatomy Link Frequency
finger 4
Egr1 (Mus musculus)
Ptges2 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 8 83.16 Quite High
Inflammation 44 69.76 Quite High
Pain 4 45.68 Quite Low
Arthritis 24 45.52 Quite Low
dexamethasone 2 36.84 Quite Low
Osteoarthritis 2 35.12 Quite Low
rheumatoid arthritis 10 33.76 Quite Low
cINOD 10 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoarthritis 6 84.32 Quite High
INFLAMMATION 36 69.76 Quite High
Pain 4 45.68 Quite Low
Arthritis 24 45.52 Quite Low
Fever 8 44.88 Quite Low
Rheumatoid Arthritis 12 33.76 Quite Low
Osteoporosis 2 26.00 Quite Low
Hypercalcemia 2 25.20 Quite Low
Disease 8 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It was recently shown that the zinc-finger-containing transcription factor, early growth response gene-1 (Egr-1) binds specifically to GC-rich elements in the mPGES-1 promoter region and facilitates murine mPGES-1 gene transcription [28].
Egr-1 Positive_regulation (facilitates) of Transcription (transcription) of mPGES-1 in finger
1) Confidence 0.08 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174970 Disease Relevance 0.21 Pain Relevance 0.11
It was recently shown that the zinc-finger-containing transcription factor, early growth response gene-1 (Egr-1) binds specifically to GC-rich elements in the mPGES-1 promoter region and facilitates murine mPGES-1 gene transcription [28].
early growth response gene-1 Positive_regulation (facilitates) of Transcription (transcription) of mPGES-1 in finger
2) Confidence 0.08 Published 2005 Journal Arthritis Res Ther Section Body Doc Link PMC1174970 Disease Relevance 0.21 Pain Relevance 0.11

General Comments

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